What is the role of Platelets in Homeostasis? Describe about the Bleeding Disorders.
What is the role of Platelets in Hemostasis? Describe the Bleeding Disorders. Introduction Hemostasis is the physiological process that stops bleeding at the site of an injury while maintaining blood in a fluid state within the vascular system. It is a critical mechanism that involves several steps to prevent excessive blood loss and to repair damaged blood vessels. Platelets, also known as thrombocytes, play a pivotal role in hemostasis. They are small, anucleate cell fragments that originate from the cytoplasm of megakaryocytes in the bone marrow. Platelets circulate in the blood and are essential for the repair of damaged blood vessels. Role of Platelets in Hemostasis Platelets contribute to hemostasis through several key functions: 1. Adhesion: Platelets adhere to the exposed collagen fibers at the site of vascular injury, forming the initial platelet plug. 2. Activation: Upon adhesion, platelets become activated and change shape, releasing granules that contain substances neces